YOUR CHILD, HIS FAMILY AND FRIENDS

The handicapped child and his family.

Histidinaemia: a child and his family.

Histidinaemia, an inherited disorder of histidine metabolism, was first described by Ghadimi, Partington, and Hunter in 1961. The principal metabolic pathway for histidine is through urocanic acid and formiminoglutamic acid (FIGLU) to glutamic acid (Fig. 1). Zannoni and La Du (1963) demonstrated that histidase, the enzyme necessary for the conversion of histidine to urocanic acid, was absent fr...

Samuel Johnson: his ills, his pills and his physician friends.

Samuel Johnson (1709-1784) was one of the greatest men of his age. Although famed for his writings, especially his Dictionary and his folio on Shakespeare, he is remembered for his tavern conversations, his literary clubs and the great biography of his life by Boswell. He always enjoyed having physicians as his friends, and took a great interest in all branches of medicine. He would advise and ...

Pseudotypes: your flexible friends.

Pseudotype viruses: applications and troubleshooting’ (EuroSciCon 2013), a 1-day conference held at Cineworld: The O2 (London, UK) on 2 October 2013, focused on the technique of pseudotyping enveloped viruses (for a review of the technique, see [1]). The talks and posters covered the challenges and successes of pseudotyping viruses from a broad range of families (Retroviridae, Flaviviridae, Ort...

Choose Your Friends Wisely

When we think of the word ‘‘contagious,’’ we often think of something negative, like the flu. But transmitted diseases aren’t the only thing that can quickly spread within a society—certain feelings, emotions, and behaviors can be easier to catch than the common cold. Does seeing others laugh or yawn make you want to do it too? You’re definitely not alone—‘‘behavioral contagion,’’ or the tenden...